Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/3 | H | Bowling Green (4-8) | [G5:MAC] | W | 77-10 | |
| 9/10 | H | Tulsa (9-3) | [G5:AAC] | W | 48-3 | |
| 9/17 | A | Oklahoma (10-2) | [P4:Big 12] | W | 45-24 | |
| 10/1 | H | Rutgers (2-10) | [P4:Big Ten] | W | 58-0 | |
| 10/8 | H | Indiana (6-6) | [P4:Big Ten] | W | 38-17 | |
| 10/15 | A | Wisconsin (10-3) | [P4:Big Ten] | W | 30-23 | |
| 10/22 | A | Penn State (11-2) | [P4:Big Ten] | L | 21-24 | |
| 10/29 | H | Northwestern (6-6) | [P4:Big Ten] | W | 24-20 | |
| 11/5 | H | Nebraska (9-3) | [P4:Big Ten] | W | 62-3 | |
| 11/12 | A | Maryland (6-6) | [P4:Big Ten] | W | 62-3 | |
| 11/19 | A | Michigan St (3-9) | [P4:Big Ten] | W | 17-16 | |
| 11/26 | H | Michigan (10-2) | [P4:Big Ten] | W | 30-27 | |
| 12/31 | N | Clemson (12-1) | [P4:ACC] | L | 0-31 | PlayStation Fiesta Bowl - CFP Semifinal * |
* game does not count in Harbin ratings