Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/1 | N | N Illinois (12-1) | [G5:MAC] | W | 18-17 | AT Chicago |
| 9/8 | H | Iowa State (6-6) | [P4:Big 12] | L | 6-9 | |
| 9/15 | H | Northern Iowa (5-6) | [FCS:MVFC] | W | 27-16 | |
| 9/22 | H | C Michigan (6-6) | [G5:MAC] | L | 31-32 | |
| 9/29 | H | Minnesota (6-6) | [P4:Big Ten] | W | 31-13 | |
| 10/13 | A | Michigan St (6-6) | [P4:Big Ten] | W | 19-16 | |
| 10/20 | H | Penn State (8-4) | [P4:Big Ten] | L | 14-38 | |
| 10/27 | A | Northwestern (9-3) | [P4:Big Ten] | L | 17-28 | |
| 11/3 | A | Indiana (4-8) | [P4:Big Ten] | L | 21-24 | |
| 11/10 | H | Purdue (6-6) | [P4:Big Ten] | L | 24-27 | |
| 11/17 | A | Michigan (8-4) | [P4:Big Ten] | L | 17-42 | |
| 11/23 | H | Nebraska (10-3) | [P4:Big Ten] | L | 7-13 |