MAC rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/3 | A | Ohio State (6-6) | [P4:Big Ten] | L | 0-42 | |
| 9/10 | H | Temple (8-4) | [G5:MAC] | L | 3-41 | |
| 9/17 | A | Cincinnati (9-3) | [P4:Big East] | L | 14-59 | |
| 9/24 | H | VMI (2-9) | [FCS:BSOU] | W | 36-13 | |
| 10/1 | A | E Michigan (6-6) | [G5:MAC] | L | 23-31 | |
| 10/8 | H | FIU (8-4) | [G5:Sun Belt] | L | 17-27 | |
| 10/22 | H | Ohio (9-4) | [G5:MAC] | L | 20-37 | |
| 10/29 | H | C Michigan (3-9) | [G5:MAC] | L | 22-23 | |
| 11/3 | A | Miami OH (4-8) | [G5:MAC] | L | 3-35 | |
| 11/12 | H | Kent State (5-7) | [G5:MAC] | L | 3-35 | |
| 11/19 | A | Buffalo (3-9) | [G5:MAC] | L | 10-51 | |
| 11/25 | A | W Michigan (7-5) | [G5:MAC] | L | 19-68 |