Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/30 | H | Utah (12-0) | [G5:MWC] | L | 23-25 | |
| 9/6 | H | Miami OH (2-10) | [G5:MAC] | W | 16-6 | |
| 9/13 | A | Notre Dame (6-6) | [P4:Ind] | L | 17-35 | |
| 9/27 | H | Wisconsin (7-5) | [P4:Big Ten] | W | 27-25 | |
| 10/4 | H | Illinois (5-7) | [P4:Big Ten] | L | 20-45 | |
| 10/11 | H | Toledo (3-9) | [G5:MAC] | L | 10-13 | |
| 10/18 | A | Penn State (11-1) | [P4:Big Ten] | L | 17-46 | |
| 10/25 | H | Michigan St (9-3) | [P4:Big Ten] | L | 21-35 | |
| 11/1 | A | Purdue (4-8) | [P4:Big Ten] | L | 42-48 | |
| 11/8 | A | Minnesota (7-5) | [P4:Big Ten] | W | 29-6 | |
| 11/15 | H | Northwestern (9-3) | [P4:Big Ten] | L | 14-21 | |
| 11/22 | A | Ohio State (10-2) | [P4:Big Ten] | L | 7-42 |