Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/30 | H | App State (7-5) | [G5:Sun Belt] | W | 52-14 | |
| 9/6 | A | Notre Dame (7-5) | [P4:Ind] | L | 0-31 | |
| 9/13 | H | Miami OH (2-10) | [G5:MAC] | W | 34-10 | |
| 9/20 | H | Utah (8-4) | [P4:Pac-12] | L | 10-26 | |
| 9/27 | H | Minnesota (8-4) | [P4:Big Ten] | L | 14-30 | |
| 10/4 | A | Rutgers (7-5) | [P4:Big Ten] | L | 24-26 | |
| 10/11 | H | Penn State (6-6) | [P4:Big Ten] | W | 18-13 | |
| 10/25 | A | Michigan St (10-2) | [P4:Big Ten] | L | 11-35 | |
| 11/1 | H | Indiana (4-8) | [P4:Big Ten] | W | 34-10 | |
| 11/8 | A | Northwestern (5-7) | [P4:Big Ten] | W | 10-9 | |
| 11/22 | H | Maryland (7-5) | [P4:Big Ten] | L | 16-23 | |
| 11/29 | A | Ohio State (12-1) | [P4:Big Ten] | L | 28-42 |