ACC rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/1 | H | Marshall (3-9) | [G5:CUSA] | W | 31-3 | |
| 9/8 | A | Oklahoma (11-2) | [P4:Big 12] | L | 13-51 | |
| 9/15 | H | FIU (1-11) | [G5:Sun Belt] | W | 23-9 | |
| 9/20 | H | Texas A&M (7-5) | [P4:Big 12] | W | 34-17 | |
| 9/29 | H | Duke (1-11) | [P4:ACC] | W | 24-14 | |
| 10/6 | A | North Carolina (4-8) | [P4:ACC] | L | 27-33 | |
| 10/13 | H | Georgia Tech (7-5) | [P4:ACC] | L | 14-17 | |
| 10/20 | A | Florida St (7-5) | [P4:ACC] | W | 37-29 | |
| 11/3 | H | NC State (5-7) | [P4:ACC] | L | 16-19 | |
| 11/10 | H | Virginia (9-3) | [P4:ACC] | L | 0-48 | |
| 11/17 | A | Virginia Tech (11-2) | [P4:ACC] | L | 14-44 | |
| 11/24 | A | Boston College (10-3) | [P4:ACC] | L | 14-28 |