Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/1 | H | Bowling Green (8-4) | [G5:MAC] | L | 31-32 | |
| 9/8 | H | Miami OH (6-7) | [G5:MAC] | W | 41-35 | |
| 9/15 | A | FAU (7-5) | [G5:Sun Belt] | L | 39-42 | AT MIAMI FL |
| 9/22 | H | Purdue (7-5) | [P4:Big Ten] | L | 31-45 | |
| 9/29 | H | Ohio State (11-1) | [P4:Big Ten] | L | 7-30 | |
| 10/6 | A | Indiana (7-5) | [P4:Big Ten] | L | 20-40 | |
| 10/13 | A | Northwestern (6-6) | [P4:Big Ten] | L | 48-49 | |
| 10/20 | H | N Dakota St (10-1) | [FCS:GWEST] | L | 21-27 | |
| 10/27 | A | Michigan (8-4) | [P4:Big Ten] | L | 10-34 | |
| 11/3 | H | Illinois (9-3) | [P4:Big Ten] | L | 17-44 | |
| 11/10 | A | Iowa (6-6) | [P4:Big Ten] | L | 16-21 | |
| 11/17 | H | Wisconsin (9-3) | [P4:Big Ten] | L | 34-41 |