Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/30 | A | Toledo (9-2) | [G5:MAC] | L | 7-38 | |
| 9/8 | H | Louisiana (3-8) | [G5:Sun Belt] | W | 44-14 | |
| 9/15 | H | Baylor (3-8) | [P4:Big 12] | canceled | ||
| 9/29 | H | Purdue (6-5) | [P4:Big Ten] | L | 28-35 | |
| 10/6 | A | Illinois (10-1) | [P4:Big Ten] | L | 14-25 | |
| 10/13 | A | Northwestern (4-7) | [P4:Big Ten] | L | 17-23 | |
| 10/20 | H | Michigan St (6-5) | [P4:Big Ten] | W | 28-19 | |
| 10/27 | H | Murray St (4-6) | [FCS:OVC] | W | 66-10 | |
| 11/3 | H | Ohio State (7-4) | [P4:Big Ten] | L | 28-31 | |
| 11/10 | A | Michigan (8-3) | [P4:Big Ten] | L | 10-31 | |
| 11/17 | A | Iowa (6-5) | [P4:Big Ten] | L | 24-42 | |
| 11/24 | H | Wisconsin (5-7) | [P4:Big Ten] | W | 42-31 |