Big 12 rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/1 | A | Southern Miss (6-5) | [G5:CUSA] | L | 9-17 | |
| 9/8 | H | Louisiana Tech (7-4) | [G5:WAC] | W | 30-23 | |
| 9/15 | H | N Arizona (8-4) | [FCS:BSKY] | canceled | ||
| 9/22 | A | Texas A&M (7-4) | [P4:Big 12] | L | 7-21 | |
| 9/29 | H | N'Western St (8-4) | [FCS:LAND] | W | 24-0 | |
| 10/6 | H | Missouri (4-7) | [P4:Big 12] | L | 38-41 | |
| 10/13 | H | Texas (10-2) | [P4:Big 12] | L | 17-45 | |
| 10/20 | A | Iowa State (7-4) | [P4:Big 12] | L | 14-28 | |
| 10/27 | H | Colorado (10-2) | [P4:Big 12] | L | 19-22 | |
| 11/10 | H | Texas Tech (7-4) | [P4:Big 12] | L | 30-49 | |
| 11/17 | A | Baylor (3-8) | [P4:Big 12] | W | 38-22 | |
| 11/24 | A | Oklahoma (10-2) | [P4:Big 12] | W | 16-13 |